Driving Progress in CHD Research: Meet Adam Armstrong
At HeartWorks, our mission to advance innovative therapies for congenital heart defects (CHD) is powered by dedicated individuals whose work connects science, patients, and families. In this Employee Spotlight, we are proud to introduce Adam Armstrong, Director of Clinical Operations at HeartWorks. Adam’s professional journey, deep ties to congenital heart disease research, and commitment to family reflect the compassion and purpose that define our organization and the Heart Warrior community we serve.
From the Midwest to a Career in Congenital Heart Disease Research
Adam was born and raised in central Indiana, where his interest in science and healthcare began early. After graduating high school, he attended Purdue University and earned a degree in Medical Technology. This academic foundation led him into the rapidly evolving world of cell therapy and clinical research that would ultimately connect him to families impacted by congenital heart defects.
Adam began his professional career in a cell therapy laboratory at Mayo Clinic, where he gained hands-on experience supporting advanced clinical research. It was during his time in the lab at Mayo Clinic that Adam met his future wife. Today, Adam and his wife are raising two daughters who keep their family busy through youth soccer, practices, and games. Outside of work, Adam enjoys spending time with his family – whether traveling together, working as a team to solve an escape room, playing board games, or enjoying a good movie night at home.
A Longstanding Connection to HLHS and HeartWorks
Adam’s connection to Hypoplastic Left Heart Syndrome (HLHS) and HeartWorks began well before he officially joined the organization. His initial involvement with HLHS programs dates back to around 2012, when he worked in a Mayo Clinic laboratory responsible for processing cord blood used in early clinical trials. This experience gave Adam a behind-the-scenes look at the complexity of clinical research for congenital heart disease and the trust families place in investigational therapies.
In 2021, Adam had the opportunity to join HeartWorks full time as Regulatory Program Manager. In this role, he supported the regulatory and operational framework necessary to responsibly conduct clinical trials for patients with congenital heart defects. In July of 2025, Adam transitioned into his current role as Director of Clinical Operations, bringing together his experience in laboratory science, regulatory oversight, and clinical trial execution to help guide HeartWorks’ growing portfolio of studies.
What Adam’s Role at HeartWorks Looks Like Day to Day
As Director of Clinical Operations, Adam plays a key role in ensuring that HeartWorks’ clinical trials run smoothly, safely, and in compliance with regulatory requirements. His day-to-day work involves close collaboration with colleagues across the organization, all focused on advancing clinical research for CHD patients and families.
Adam works alongside teams to manage the operational responsibilities of running clinical trials, from planning and coordination to execution and oversight. He also spends time supporting the Co-op @ HeartWorks, an innovative collaborative platform designed to advance regenerative medicine and accelerate research progress. Whether problem-solving, planning for upcoming studies, or aligning teams around shared goals, Adam’s role centers on teamwork and precision in support of patients.
Finding Inspiration in the Heart Warrior Community
For Adam, one of the most inspiring aspects of working at HeartWorks is the Heart Warrior community itself. Families impacted by congenital heart defects consistently demonstrate resilience, generosity, and strength. These qualities motivate and energize the work being done every day.
Inspiration comes through many channels: stories shared online, conversations during visits to HeartWorks, and handwritten cards expressing appreciation for ongoing research efforts. These moments serve as powerful reminders that behind every clinical trial, protocol, and data point are real children and families placing hope in scientific progress. Being part of this mission is a source of pride and responsibility for Adam.
Passion for Family, Teamwork, and Connection
Outside of work, Adam is most passionate about spending quality time with his family. Whether traveling together or tackling activities that require teamwork and communication, these moments reinforce the importance of collaboration and trust – values that also guide his professional approach at HeartWorks.
Family life provides perspective and balance, grounding Adam in the “why” behind the work: creating better futures for children and families affected by congenital heart disease.
Looking Ahead: Innovation, Participation, and What’s Next
Looking to the future, Adam is excited by the growing participation in HeartWorks’ clinical trials, including more recent studies such as the skin punch biopsy trial. This level of engagement from patients and families highlights a shared commitment to advancing research and exploring new therapeutic options for congenital heart defects.
Adam is particularly hopeful about the possibilities that remain unexplored in CHD research. Each study builds momentum, expanding the potential for future therapies and strengthening the foundation for innovation in regenerative medicine.
A Shared Mission of Science and Compassion
Adam Armstrong’s journey at HeartWorks reflects the organization’s core values by combining rigorous science with compassion, collaboration, and respect for the families at the heart of this work. Through his leadership and dedication, Adam helps ensure that HeartWorks remains focused on advancing meaningful research while honoring the trust of patients, families, and caregivers seeking hope in the face of congenital heart disease.
Together, Adam and the HeartWorks team remain committed to shaping a future defined by innovation, empathy, and progress for the CHD community.
FAQs: Clinical Research and Study Opportunities at HeartWorks
What types of studies is HeartWorks working on?
HeartWorks is advancing research focused on congenital heart disease, including regenerative medicine studies, clinical readiness programs, and patient-specific research initiatives.
What is the skin punch biopsy study?
The skin punch biopsy study collects patient cells that may help support future regenerative medicine research and personalized approaches for congenital heart disease.
What is The Co-op @ HeartWorks?
The Co-op @ HeartWorks is a collaborative platform designed to connect patients, families, and research while helping accelerate innovation and future study opportunities.
Why is participation in CHD research important?
Research participation helps scientists better understand congenital heart disease and supports the development of future therapies and treatment approaches.
How can families learn about future study opportunities?
The best way families can stay connected about the opportunities available for them is through The Co-op @ HeartWorks. The Co-op will alert you specifically when you are eligible. Additional ways include: newsletters, webinars, and updates shared by the HeartWorks team.
What role does clinical operations play in research?
Clinical operations teams help ensure studies are conducted safely, responsibly, and in alignment with regulatory requirements while supporting participating families throughout the process.
Does participation guarantee access to future therapies?
Participation in research does not guarantee access to future treatments, but it helps advance scientific understanding and future possibilities for congenital heart disease care.


